NVIDIA and Palantir Partner on Integrated AI Stack for Enterprises and Government
The goal is to help organizations use their data to create AI-driven automations and domain-specific agents.
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NVIDIA has tied up with Palantir Technologies to develop an integrated technology stack designed to accelerate “operational AI” across industries.
The partnership brings together Palantir’s AI Platform (AIP) and NVIDIA’s GPU-accelerated computing and Nemotron open AI models to support complex enterprise and government systems.
At the core of this initiative is Palantir’s Ontology, a digital model that organizes enterprise data and logic, now enhanced with NVIDIA’s CUDA-X data processing, optimization software, and Nemotron open AI models.
The goal is to help organizations use their data to create AI-driven automations and domain-specific agents for use cases in retail, healthcare, finance, and the public sector.
“Palantir and NVIDIA share a vision: to put AI into action, turning enterprise data into decision intelligence,” said Jensen Huang, founder and CEO of NVIDIA.
Palantir cofounder and CEO Alex Karp said the partnership would help deliver “immediate, asymmetric value” to customers through AI-enabled decision systems.
Among the first adopters of the technology stack is Lowe’s, which is building a digital twin of its global supply chain network. The home improvement retailer plans to use AI to dynamically optimize operations and respond faster to market shifts.
“Even small shifts in demand can create ripple effects across the global network. By combining Palantir technologies with NVIDIA AI, Lowe’s is reimagining retail logistics,” said Seemantini Godbole, EVP and chief digital and information officer at Lowe’s.
The collaboration will also integrate NVIDIA’s latest AI hardware and models, including the upcoming Blackwell architecture and NeMo Retriever, into Palantir’s AIP ecosystem. These integrations are expected to power more advanced, reasoning-based AI agents and improve real-time decision-making for critical workflows.
Palantir AIP will also feature in NVIDIA’s newly announced AI Factory for Government reference design, aimed at helping public sector organizations deploy secure, high-performance AI systems.

